sFlt-1 Elecsys | REF 5109523190

The Roche Elecsys sFlt-1 assay (REF 5109523190) is an electrochemiluminescence immunoassay (ECLIA) reagent kit developed for the in vitro quantitative determination of soluble fms-like tyrosine kinase-1 (sFlt-1) in human serum and plasma. The assay is intended for use on Roche cobas e immunoassay analyzers and forms part of the Elecsys preeclampsia testing portfolio, typically used in conjunction with the Elecsys PlGF assay to calculate the sFlt-1/PlGF ratio.

Key Features
- Methodology: Sandwich electrochemiluminescence immunoassay (ECLIA) using biotinylated and ruthenium-labeled monoclonal antibodies against sFlt-1.
- Sample material: Human serum and lithium-heparin or K2/K3-EDTA plasma.
- Total assay duration: Approximately 18 minutes.
- Calibration: 2-point calibration with traceability to the manufacturer's master calibrator.
- Format: Ready-to-use reagent rackpack containing streptavidin-coated microparticles and anti-sFlt-1 antibody reagents.
- Storage: Refrigerated storage as defined in the official Roche Method Sheet / IFU.

Clinical Applications
- Quantitative measurement of circulating sFlt-1 levels in pregnant women.
- Use as part of the sFlt-1/PlGF ratio in the assessment of hypertensive disorders of pregnancy, including preeclampsia, in line with the official Instructions for Use.
- Laboratory workflow integration on Roche cobas e analyzers within hospital, reference, and specialty obstetric laboratories.

Product Information
- Brand: Roche
- Product line: Elecsys
- Analyte: sFlt-1 (soluble fms-like tyrosine kinase-1)
- Category: Roche Reagents
- REF / UPN: 5109523190
- Pack size and number of tests: Not specified in the located sources
- Compatible analyzers: Roche cobas e immunoassay analyzers (specific platform compatibility per official Roche documentation)
- Regulatory status and intended use: Refer to the official Roche Instructions for Use (IFU) and local regulatory labeling.

REF / UPN5109523190
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