Free beta-HCG Elecsys | REF 4854071200

The Roche Elecsys Free beta-HCG reagent (REF 4854071200) is an electrochemiluminescence immunoassay (ECLIA) designed for the in vitro quantitative determination of the free beta subunit of human chorionic gonadotropin (free β-hCG) in human serum. The assay is intended for use on Roche cobas e immunoassay analyzers and is commonly applied as part of first-trimester prenatal screening protocols in combination with other biochemical and ultrasound markers.

Key Features
- Methodology: Sandwich electrochemiluminescence immunoassay (ECLIA) using biotinylated monoclonal anti-β-hCG and ruthenium-labeled monoclonal anti-β-hCG antibodies.
- Specificity: Selective detection of the free beta subunit of hCG, minimizing cross-reactivity with intact hCG.
- Sample Material: Human serum; tube and volume requirements as specified in the official Method Sheet.
- Calibration & QC: Compatible with dedicated Elecsys CalSet and PreciControl materials supplied separately.
- Platform Compatibility: For use on Roche cobas e immunoassay analyzers as listed in the current Roche product matrix.
- Ready-to-use Reagent Pack: Cassette-format reagents for streamlined onboard handling and traceability.

Clinical Applications
- First-Trimester Prenatal Screening: Quantitative measurement of free β-hCG as part of combined screening strategies for fetal aneuploidies, used together with PAPP-A and ultrasound markers.
- Laboratory Workflow Integration: Routine use in centralized clinical chemistry and prenatal screening laboratories operating Roche cobas e immunoassay platforms.
- Risk Calculation Software: Results may be transferred to validated risk-assessment software for prenatal screening interpretation.

Product Information
- Product: Elecsys Free beta-HCG
- Manufacturer: Roche Diagnostics
- REF / UPN: 4854071200
- Category: Roche Reagents / Immunoassay
- Assay Technology: Electrochemiluminescence Immunoassay (ECLIA)
- Analyte: Free beta subunit of human chorionic gonadotropin (free β-hCG)
- Sample Type: Human serum
- Tests per Kit: Not specified in the located sources
- Storage Conditions: Refer to the official Roche Method Sheet / package insert
- Intended Use: In vitro diagnostic use on compatible Roche cobas e analyzers; refer to the official Instructions for Use for full performance characteristics, regional availability and regulatory status.

REF / UPN4854071200
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